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Synthesis of 2-substituted benzimidazoles by iodine-mediated condensation of orthoesters with 1,2-phenylenediamines

✍ Scribed by Zhan-Hui Zhang; Jian-Jiong Li; Yuan-Zhe Gao; Yu-Heng Liu

Book ID
102340251
Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
234 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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Iodine was found to be an efficient catalyst for the synthesis of 2‐substituted benzimidazoles by the condensation of orthoesters and 1,2‐phenylenediamines in good to excellent yields under mild reaction conditions.

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