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Synthesis of 2-Substituted 6-(Hydroxymethyl)purine Bases and Nucleosides

✍ Scribed by Šilhár, Peter; Pohl, Radek; Votruba, Ivan; Hocek, Michal


Book ID
111905418
Publisher
UOCHB
Year
2005
Tongue
English
Weight
221 KB
Volume
70
Category
Article
ISSN
0010-0765

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Synthesis of 2-Substituted 6-(Hydroxymet
✍ Peter Silhar; Radek Pohl; Ivan Votruba; Michal Hocek 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

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Synthesis of (purin-6-yl)methylphosphona
✍ Zbyněk Hasník; Radek Pohl; Michal Hocek 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 318 KB

Three approaches to the synthesis of the title (purin-6-yl)methylphosphonates were investigated and compared. While, the Arbuzov reaction of 6-(iodomethyl)purines with triethyl phosphite did not work, Michaelis-Becker alkylation of the sodium salt of diethyl phosphonate with 6-(mesyloxymethyl)purine