Synthesis of 2‘- O -[2-[( N,N -Dimethylamino)oxy]ethyl] Modified Nucleosides and Oligonucleotides
✍ Scribed by Prakash, Thazha P.; Kawasaki, Andrew M.; Fraser, Allister S.; Vasquez, Guillermo; Manoharan, Muthiah
- Book ID
- 121224873
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 172 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
Synthesis of a series of 2 0 -O-[2-[(N,N-dialkylamino)oxy]ethyl]-modified 5-methyluridine nucleoside phosphoramidites and solid supports are described. Using these monomers, modified oligonucleotides containing phosphodiester linkages were synthesized in high yields. These modified oligonucleotides
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