Synthesis of 2-methyl and 2-carboxymethyl derivatives of ornithine and arginine
โ Scribed by UNSON, CECILIA G. ;ERICKSON, BRUCE W.
- Book ID
- 115097951
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 498 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0367-8377
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๐ SIMILAR VOLUMES
Abstn&--A l?riedel-&& condensation of l,?-~~ox~aph~~e with the anhydride IV gave a mixture of products from which, after ester&&on, the ketoestem IX and X could be isolated in 16 and 4.25 % yield, respectively. These were hydrogenolysed with Pd-C to the desoxyesten XI and XII. Cyclodehydration of th
3'-a-Carboxymethyl-2"O-methyl ribonucleosides, which are important building blocks for the construction of high affinity amide modified antisense oligonucleotides, have been synthesized from the corresponding 2'-O-methyl ribonucleosides via catalytic hydrogenation of their 3'-deoxy 3'-methoxycarbony