The reactions of methyl glyoxylate hemiacetal 1 with 2-(methy1amino)ethanol 2, ( I R,2S)-( -)-ephedrine 3 and (IS,2S)-( +) -pseudoephedrine 4 provide the (2s)-2-hydroxy-l,4-oxazin-3-ones 2% 3% 4a i n good yield. They were characterized by 'H, I3C, NMR, and infrared and mass spectroscopy. The structu
✦ LIBER ✦
Synthesis of 2-Hydroxy-1,4-oxazin-3-ones through Ring Transformation of 3-Hydroxy-4-(1,2-dihydroxyethyl)-β-lactams and a Study of Their Reactivity
✍ Scribed by Mollet, Karen; Goossens, Hannelore; Piens, Nicola; Catak, Saron; Waroquier, Michel; Törnroos, Karl W.; Van Speybroeck, Veronique; D'hooghe, Matthias; De Kimpe, Norbert
- Book ID
- 119958041
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 878 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0947-6539
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