## Abstract For Abstract see ChemInform Abstract in Full Text.
SYNTHESIS OF 2′-DEOXY-2′-FLUORO- 1-β- d -ARABINOFURANOSYL URACIL DERIVATIVES: A METHOD SUITABLE FOR PREPARATION OF [ 18 F]-LABELED NUCLEOSIDES
✍ Scribed by Alauddin, Mian M.; Conti, Peter S.; Fissekis, John D.; Watanabe, Kyoihci A.
- Book ID
- 121693413
- Publisher
- Taylor and Francis Group
- Year
- 2002
- Tongue
- English
- Weight
- 188 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0039-7911
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📜 SIMILAR VOLUMES
The synthesis of t h e title canpound (7) is described. [2-14C] cytosine (I) is treated with an aqueous mixture of sodium bisulfite and sodium sulfate at 8OoC for 30 rnin. The resulting solid is then treated with aqueous sodiun hydroxide and passed through a cation exchange colunn, producing [ Z-14C
## Abstract Synthesis of 2′‐deoxy‐2′‐[^18^F]fluoro‐5‐methyl‐1‐__β__‐D‐arabinofuranosyluracil ([^18^F]‐FMAU) is reported. 2‐Deoxy‐2‐[^18^F]fluoro‐1,3,5‐tri‐O‐benzoyl‐__α__‐D‐arabinofuranose **2** was prepared by the reaction of the respective triflate **1** with tetrabutylammonium[^18^F]fluoride. Th