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Synthesis of 2-Arylacrylates from Pyruvate by Tosylhydrazide-Promoted Pd-Catalyzed Coupling with Aryl Halides

✍ Scribed by Prof. José Barluenga; María Tomás-Gamasa; Prof. Fernando Aznar; Dr. Carlos Valdés


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
161 KB
Volume
16
Category
Article
ISSN
0947-6539

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Efficient Synthesis of 1,1-Diaryl 1,2-Dienes via Pd(0)-Catalyzed Coupling of Aryl Halides with Allenic/Propargylic Zinc Reagents. -The title reaction is proposed to involve oxidative addition of halides to Pd(0) to form an organopalladium intermediate. This is trapped by an allenic or propargylic z