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Synthesis of 2-aryl-4-phenyl-5-trifluoromethylimidazoles

✍ Scribed by Joseph G. Lombardino

Book ID: 112123016
Publisher: Journal of Heterocyclic Chemistry
Year: 1973
Tongue: English
Weight: 134 KB
Volume: 10
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570100502

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## Abstract The synthesis of potential fluorescent active 4‐(5‐aryl‐1,3,4‐oxadiazol‐2‐yl)phenylhydrazine derivatives was accomplished in three steps. The key step was the dehydration cyclization of 1,2‐diacylhydrazines to form the 1,3,4‐oxadiazole ring by use of acetic anhydride/perchloric acid mix