Synthesis of 2-aroylmethyl-5-phenyl-1,3,4-thiadiazoles
โ Scribed by T. E. Glotova; A. S. Nakhmanovich; T. N. Komarova
- Publisher
- Springer US
- Year
- 1988
- Tongue
- English
- Weight
- 64 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0009-3122
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๐ SIMILAR VOLUMES
Acyl chlorides are split into acyl and chlorine radicals by light of wavelength 254 my. Since the dissociation energy of the chlorine-hydrogen bond is considerably larger than that of the acyl-hydrogen bond, substitution of the substrate by acyl radicals is observed on irradiation of acid chlorides.
The title compound, C~13~H~12~N~4~O~3~S~3~, was synthesized __via__ condensation of 1,2,4-oxadiazole chloromethane with 1,3,4-thiadiazolethiol. There are three rings in the molecule. The benzene and oxadiazole rings are coplanar due to the extended aromatic system. The angle between this plane and t