Synthesis of 2-aminochromene derivatives catalyzed by KF/Al2O3

✍ Scribed by Xiang-Shan Wang; Da-Qing Shi; Shu-Jiang Tu

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 246 KB
• Volume: 21
• Category: Article
• ISSN: 0256-7660
• DOI: 10.1002/cjoc.20030210903

✦ Synopsis

Abstract

A series of 2‐aminochromene derivatives including 2‐amino‐benzo[h] chromene, 2‐amino‐benzo [f] chromene and 2‐aminopyrano [3, 2‐h] quinolin derivatives was synthesized from arylaldehyde, malononitrile or ethyl cyanoacetate and 1‐naphthol or 2‐naphthol or 8‐hydroxyquinoline in refluxing ethyl alcohol catalyzed by KF‐Al~2~O~3~. The structures were confirmed by X‐ray analysis.