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Synthesis of 2-Alkoxy(aroxy)-3-substituted Quinolines by DABCO-Promoted Cyclization of o -Alkynylaryl Isocyanides

โœ Scribed by Zhao, Jiaji; Peng, Changlan; Liu, Lanying; Wang, Yong; Zhu, Qiang


Book ID
120920863
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
768 KB
Volume
75
Category
Article
ISSN
0022-3263

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Cyclization of hydroxy epoxides promoted
โœ Ryuji Matsumura; Toshio Suzuki; Kohki Sato; Ken-ichi Oku; Hisahiro Hagiwara; Tak ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 64 KB

Cyclization of hydroxy epoxides mediated by a (Bu 3 Sn) 2 O/Lewis acid system proceeded via an S N 2 process and exo mode to provide the corresponding seven-membered cyclic ethers in high yield.