ChemInform Abstract: Synthesis of 2-Acet
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Alison T. Ung; Stephen G. Pyne; George R. Jeoffreys; Brian W. Skelton; Allan H.
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Article
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2011
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John Wiley and Sons
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## Abstract The synthesis of two diastereomers of the title compound involves the coupling of 5βlithiated 2β(1,1βdimethoxyethyl)thiazole (VI) with a Weinreb amide (V) derived from gluconolacetone, followed by asymmetric reduction of the ketone functionality.