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Synthesis of 2-(4-substituted benzyl-1,4-diazepan-1-yl)-N-(3,4-dihydro-3-oxo-2H-benzo[b][1,4]oxazin-7-yl)acetamides and their positive inotropic evaluation

✍ Scribed by Kun Yang; Liang-Peng Sun; Ji-Yong Liu; Xun Cui; Hu-Ri Piao


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
241 KB
Volume
20
Category
Article
ISSN
0960-894X

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In the title compound, C 19 H 15 FI 2 N 2 O 4 , the cyclohexene and morpholinone rings adopt half-chair conformations. The dihedral angle between the benzene and pyrrole rings is 69.0 (2) . The crystal packing is stabilized by C-HÁ Á ÁO and C-HÁ Á ÁF hydrogen bonds. ## Related literature For gene