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Synthesis of 2-(3-indolyl)-1,4-naphthoquinones using 3-iodoindoles

✍ Scribed by Yasuhiro Tanoue; Moritsugu Hamada; Norihisa Kai; Kazunori Sakata; Mamoru Hashimoto; Takeshi Nagai

Publisher: Journal of Heterocyclic Chemistry
Year: 2005
Tongue: English
Weight: 92 KB
Volume: 42
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570420625

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✦ Synopsis

The usefulness of 3-iodoindoles available for introduction of an indole unit is presented. The reaction of various halo-3-iodoindoles with 1,4-naphthoquinone gave the corresponding 2-(3-indolyl)-1,4-naphthoquinones in moderate yields. The 3-iodoindole was used for synthesis of a compound containing both naphthazarin and indole skeletons.

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