𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of (19R)-19-hydroxy-PGE and -PGF prostaglandins

✍ Scribed by John C. Sih

Book ID
119048458
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
146 KB
Volume
13
Category
Article
ISSN
0090-6980

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Enantioselective Synthesis of (βˆ’)-(19R)-
Enantioselective Synthesis of (βˆ’)-(19R)-Ibogamin-19-ol
✍ Stefan HΓΆck; Hans-JΓΌrg Borschberg πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 German βš– 203 KB

## Abstract The first total synthesis of the natural product (βˆ’)‐(19__R__)‐ibogamin‐19‐ol ((βˆ’)‐**1**) is reported (biogenetic atom numbering). Starting with L‐glutamic acid from the chiral pool and (2__S__)‐but‐3‐en‐2‐ol, the crucial aliphatic isoquinuclidine (= 2‐azabicyclo[2.2.2]octane) core cont