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Synthesis of 15N-5-doxylstearic acid for improved EPR characterization of lipid motion in biomembranes

✍ Scribed by Sindhaghatta D. Venkataramu; Donald E. Pearson; Albert H. Beth; K. Balasubramanian; Charles R. Park; Jane H. Park

Book ID: 102369769
Publisher: John Wiley and Sons
Year: 1983
Tongue: French
Weight: 403 KB
Volume: 20
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580200402

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✦ Synopsis

15N-5-Doxylstearic acid has been synthesized to improve EPR spectral characterization of the motional properties of the lipid in biological membranes.

The EPR spectrum of the title compound displayed a 1.73 fold gain in sensitivity compared with the corresponding label substituted with the common isotope of nitrogen.

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