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Synthesis of 14C-meglumine salicylate and its disposition in humans after oral administration

✍ Scribed by Nagy A. Farid; Gordon S. Born; Wayne V. Kessler; Henry T. Russell; Stanley M. Shaw; Winthrop E. Lange

Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
382 KB
Volume
66
Category
Article
ISSN
0022-3549

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Absorption and disposition including enterohepatic circulation of (14C) roquinimex after oral administration to healthy volunteers
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The absorption and disposition of roquinimex (Linomide) were studied in four male and two female healthy volunteers. The subjects received a single oral aqueous solution of 14C-labelled roquinimex, about 0.1 mg/kg, after an overnight fast. Blood samples were taken and urine and faeces were collected