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Synthesis of 1,4-Naphthoquinone Methides via Acid-Catalyzed Cascade Cyclizations of Benzannulated Enediynyl Alcohols

โœ Scribed by Wen, Bo; Petersen, Jeffrey L.; Wang, Kung K.


Book ID
120523192
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
270 KB
Volume
13
Category
Article
ISSN
1523-7060

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6H-Naphtho[2,3-c] chromene-7,12-diones, to be considered as tetracyclic derivatives of the natural product pentalongin, were conveniently synthesized for the first time via palladium-catalyzed intramolecular cyclization of 2-bromo-3-aryloxymethyl-1,4naphthoquinones.