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Synthesis of 1,3-oxathiolane-2-thiones by the reaction of steroidal oxiranes with carbon disulfide

โœ Scribed by Shamsuzzaman; Anwar Salim


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
113 KB
Volume
38
Category
Article
ISSN
0040-4039

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## Abstract The SnCl~4~โ€catalyzed reaction of (โˆ’)โ€thiofenchone (=1,3,3โ€trimethylbicyclo[2.2.1]heptaneโ€2โ€thione; **10**) with (__R__)โ€2โ€phenyloxirane ((__R__)โ€**11**) in anhydrous CH~2~Cl~2~ at โˆ’60ยฐ led to two spirocyclic, stereoisomeric 4โ€phenylโ€1,3โ€oxathiolanes **12** and **13** __via__ a regiosel