✦ LIBER ✦

Synthesis of 13-ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (desogestrel) and its main metabolite 3-oxo desogestrel

✍ Scribed by Sigfrid Schwarz; Sven Ring; Gisela Weber; Gerhard Teichmüller; Hans-Joachim Palme; Carmen Pfeiffer; Bernd Undeutsch; Bernd Erhart; Detlef Grawe

Publisher: Elsevier Science
Year: 1994
Tongue: French
Weight: 903 KB
Volume: 50
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(01)89263-2

No coin nor oath required. For personal study only.

✦ Synopsis

Absrracf: A synthesis of the steroid hormone desogestrel (25) from the lla-homo steroid 1 is described. 25 was transformed into 3-0~0 desogestrel(28) by ally1 oxidation.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of 13-Eth

ChemInform Abstract: Synthesis of 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol.

✍ H. GAO; X. SU; L. ZHOU; Z. LI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

A partial synthesis of 13-ethyl-11-methy

A partial synthesis of 13-ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (desogestrel) based upon intramolecular oxidation of an 11β-hydroxy-19-norsteroid to the 18 → 11β-lactone

✍ M. J. van den Heuvel; C. W. van Bokhoven; H. P. de Jongh; F. J. Zeelen 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 414 KB