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Synthesis of 1,3-Disubstituted Hexahydropyrimidine Derivatives from Dibenzoylmethane, Acetylacetone, Ethyl Acetoacetate: One-Pot FeCl 3 -Catalyzed Mannich Reaction

โœ Scribed by Saleh, Abdullah; Morton, Martha; D'Angelo, John


Book ID
125810872
Publisher
Taylor and Francis Group
Year
2014
Tongue
English
Weight
254 KB
Volume
44
Category
Article
ISSN
0039-7911

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## Abstract The iminium intermediate formed by the reaction of a secondary amine with acetaldehyde was reacted by (__N__โ€isocyanimino) triphenylphosphorane in the presence of an electronโ€poor (__E__)โ€cinnamic acid derivative to give the corresponding iminophosphorane intermediate, whose intramolecu