Synthesis of [1,2,3]-triazolo[1,5-a][1,4]benzodiazepines via an unprecedented one-pot Cu-catalyzed azidation–cyclization reaction
✍ Scribed by Hooyberghs, Geert; De Coster, Hendrik; Vachhani, Dipak D.; Ermolat'ev, Denis S.; Van der Eycken, Erik V.
- Book ID
- 120162171
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 408 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
## Abstract Novel polysubstituted ‐1,5‐benzothiazepine, ‐1,5‐benzoxazepine, and ‐1,5‐benzodiazepine were prepared in good yields by the reaction of hydrazono derivatives with __o__‐thioaminophenol, __o__‐aminophenol and __o__‐phenylenediamine __via__ a one‐pot reaction.
## Abstract Coupling of active [(4‐oxo‐6‐phenyl‐3__H__‐pyrimidin‐2‐yl)thio]methine compounds (**3**) with diazotized anilines in the presence of base gave [1,2,4]triazolo[4,3‐a]pyrimidines (**7**). The latter products were also obtained by reactions of hydrazonoyl chlorides (**10**) with either 6‐p