Synthesis of 1,2,3-triarylpyrroles from 1-benzylbenzotriazoles via [1 + 2 + 2] annulation
✍ Scribed by Alan R. Katritzky; Zouquan Wang; Jianqing Li; Julian R. Levell
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1997
- Tongue
- English
- Weight
- 177 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
1,2,3‐Triarylpyrroles 7 have been synthesized by sequential lithiation and alkylation of 1‐benzylbenzo‐triazoles 1 with 2‐bromoacetaldehyde diethyl acetal (2) and N‐benzylideneaniline (4), followed by treatment with formic acid in ethanol.
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