𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of 1,1,1-ethanetriacetonitrile1, precursor of 6-Substituted-4-methyl-2-aminopyridines

✍ Scribed by Stéphane Mathé; André Rassat


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
96 KB
Volume
39
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


l,l,l-ethanetfiacetonitrile la, a new symmetrical tridentate ligand has been prepared from 3methylpentenedioic acid diethylester. 6-Substituted-4-methyi-2-aminopyridines were obtained through organometallic additions on la.


📜 SIMILAR VOLUMES


Synthesis of Substituted 1,2-Dihydro-2-i
✍ Ivanov, Ivo Christov ;Stoyanov, Edmont Vassilev ;Denkova, Pavletta Stoyanova ;Di 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 470 KB

## Abstract Vilsmeier formylation of the 4‐amino‐2‐pyridinones 4a–d leads to the formation of the corresponding 3‐carbaldehydes 5a–d (the diformylated product 8 is isolated as a by‐product). A cyclizing Knoevenagel reaction of 5 with CH‐acidic nitriles 6 in the presence of piperidine gives substitu