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Synthesis of 1-substituted 3,5-diaryl-2-pyrazolines by the reaction of α,β-unsaturated ketones with hydrazines

✍ Scribed by Albert Lévai; József Jekö


Publisher
Journal of Heterocyclic Chemistry
Year
2006
Tongue
English
Weight
99 KB
Volume
43
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

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1‐Acetyl‐, 1‐propionyl‐ and 1‐phenyl‐3,5‐diaryl‐2‐pyrazolines have been synthesized by the reaction of the appropriate α,β‐unsaturated ketones with hydrazine or phenylhydrazine in hot acetic acid or propionic acid. Structures of all new 2‐pyrazolines 16‐40 have been elucidated by microanalyses, ^1^H and ^13^C nmr spectroscopies.


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Synthesis of 1-substituted 5-aryl-3-styr
✍ Albert Lévai; József Jekó 📂 Article 📅 2006 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 411 KB

The reaction of dibenzylideneacetones or E,E-cinnamylidene-acetophenones and hydrazine hydrate provided 1-propionyl derivatives of 5-aryl-3-styryl-2-pyrazolines and 3-aryl-5-styryl-2-pyrazolines. These unsaturated ketones afforded 1-(2-carboxyphenyl) or 1-(4-carboxyphenyl) 5-aryl-3-styryl-2-pyrazoli