Synthesis of 1-substituted 3,5-diaryl-2-pyrazolines by the reaction of α,β-unsaturated ketones with hydrazines
✍ Scribed by Albert Lévai; József Jekö
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2006
- Tongue
- English
- Weight
- 99 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
magnified image
1‐Acetyl‐, 1‐propionyl‐ and 1‐phenyl‐3,5‐diaryl‐2‐pyrazolines have been synthesized by the reaction of the appropriate α,β‐unsaturated ketones with hydrazine or phenylhydrazine in hot acetic acid or propionic acid. Structures of all new 2‐pyrazolines 16‐40 have been elucidated by microanalyses, ^1^H and ^13^C nmr spectroscopies.
📜 SIMILAR VOLUMES
The reaction of dibenzylideneacetones or E,E-cinnamylidene-acetophenones and hydrazine hydrate provided 1-propionyl derivatives of 5-aryl-3-styryl-2-pyrazolines and 3-aryl-5-styryl-2-pyrazolines. These unsaturated ketones afforded 1-(2-carboxyphenyl) or 1-(4-carboxyphenyl) 5-aryl-3-styryl-2-pyrazoli