Synthesis of 1-phenyl-2,2-difluoro-3,3-bis(trifluoromethyl)aziridine
โ Scribed by Yu. V. Zeifman; L. T. Lantseva
- Book ID
- 112444239
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 118 KB
- Volume
- 35
- Category
- Article
- ISSN
- 1573-9171
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๐ SIMILAR VOLUMES
A convenient process for the preparation of the secondary amine 6, 2-(S)-(3,5-bis(trifluoromethyl)benzyloxy)-3-(S)-phenyl-l,4-oxazine, is described starting from the readily available (S)-phenylglycine 1. The process features efficient construction of the homochiral oxazinone intermediate 3 and ster
## Abstract 2-[3-(Trifluoromethyl)phenyl]-4,5-dihydrofuro[3,2-c]pyridin-4-one (I) was prepared by a three-step synthesis. Its reaction with phosphorus sulfide rendered thione II which was methylated to 2-[3-(Trifluoromethyl)phenyl]-4-methylsulfanylfuro[3,2-c]pyridine (III). 5-Methyl-2-[3-(trifluoro