Synthesis of 1-(N-ethoxycarbonylamino)alkylphosphonic monoesters
β Scribed by H. Liu; J. X. Xu
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 80 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0939-4451
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## Abstract A convenient diastereoselective synthesis of diisopropyl (2__R__,3__R__)β3β{{{(__R__/__S__)βaryl[(diethoxyphosphinyl)amino]methyl}hydroxyphosphinyl}oxy}β2βhydroxybutanedioate through __Mannich__βtype reactions is reported. The reactions take place under mild conditions in good yields, a