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Synthesis of 1-methyl-2-phenylcarbamoylpyrazolidines as potential anticonvulsant agents

โœ Scribed by Milton J. Kornet


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
243 KB
Volume
67
Category
Article
ISSN
0022-3549

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โœ Ching-Hsin Kung; John N.D. Wurpel; Chul-Hoon Kwon ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 130 KB ๐Ÿ‘ 2 views

A series of (S)-(+)-5-n-propyl-2-iminohydantoins with various N-1 substituents were synthesized and tested for anticonvulsant activity to better understand the structure-activity relationship (SAR) of 2-iminohydantoins. Compounds with N-1 phenoxycarbonyl (2), ethoxycarbonyl (6), t-butoxycarbonyl (7)