Synthesis of 1-Methyl-1H-pyrrole Derivatives Containing Carbonyl and Sulfamide Fragments.
โ Scribed by A. V. Skorenko; M. V. Dorogov; D. B. Kobylinskii; K. V. Balakin; D. V. Kravchenko; Bushmeleva A. A. Bushmeleva A. A.
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 17 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
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๐ SIMILAR VOLUMES
Non-steroidal 1-methyl-1H-pyrrole-2-carbonitrile containing tetrahydronaphthalenes and acyclic derivatives were evaluated as novel series of progesterone receptor (PR) antagonists using the T47D cell alkaline phosphatase assay. Moderate to potent PR antagonists were achieved with these scaffolds. Se
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