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Synthesis of [1-isoleucine-, 3-proline-, and 5-alanine]-angiotensins. II

✍ Scribed by Khosla, M. C.; Chaturvedi, N. C.; Smeby, R. R.; Bumpus, F. M.


Book ID
126924163
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
548 KB
Volume
7
Category
Article
ISSN
0006-2960

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## Abstract The synthesis of the polyhalogenated phenylalanines Phe(3β€²,4β€²,5′‐Br~3~) (**3**), Phe(3β€²,5′‐Br~2~‐4′‐Cl) (**4**) and DL‐Phe (2β€²,3β€²,4β€²,5β€²,6′‐Br~5~) (**9**) is described. The trihalogenated phenylalanines **3** and **4** are obtained stereospecifically from Phe(4′‐NH~2~) by electrophilic b