Synthesis of 1-isocyano sugars
✍ Scribed by Paul Boullanger; Gérard Descotes
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- French
- Weight
- 163 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The substitution of 1-halogeno sugars with sodium or mercuric cyanide generally yields 1 -cyano sugars 1,2,3,4,5,6 or with vicinal participating groups (acetates, benzoates). cyano orthoesters 798 . ACTON et al
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## Abstract The Ugi four‐component condensation between cycloalkanones, isocyanides, and ammonium formate affords __N__‐substituted 1‐formylamino‐1‐cycloalkanecarboxamides 1 which are dehydrated to give the corresponding isocyanides 2. Compounds 2 are cyclized with arylsulfenyl thiocyanates to 1,3‐