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Synthesis of 1-Hydroxymethylene-1,1-bis(phosphonic acids) from Acid Anhydrides: Preparation of a New Cyclic 1-Acyloxymethylene-1,1-bis(phosphonic acid)

โœ Scribed by Erwann Guenin; Estelle Degache; Jean Liquier; Marc Lecouvey


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
124 KB
Volume
2004
Category
Article
ISSN
1434-193X

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Stereochemical aspects of the hypophosph
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## Abstract Terephthalic Schiff bases react with hypophosphorous acid to form 1,4โ€phenyleneโ€bisโ€__N__โ€alkylโ€aminomethanephosphonous acids in moderate yields. NMR studies demonstrated thatโ€”for several examplesโ€”this reaction led to the exclusive formation of only one diastereomeric form. NMR investig