Synthesis of 1-Heteroaryl- and 1,3-Bis(heteroaryl)azulenes: Electrophilic Heteroarylation of Azulenes with the Triflates of N-Containing Heteroarenes
✍ Scribed by Taku Shoji; Shunji Ito; Jyunya Higashi; Noboru Morita
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 838 KB
- Volume
- 2011
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract An efficient synthesis of 5‐heteroaryl‐ and 5,7‐bis(heteroaryl)azulene derivatives was established for first time. The reaction proceeded through electrophilic substitution of 1,3‐di‐__tert__‐butylazulene (**1**) with the triflates of N‐containing heterocycles, in the presence of excess
## Abstract 1‐Azulenyl methyl sulfide reacts with highly electrophilic trifluoromethanesulfonates of __N__‐heterocycles, that is, pyridine, isoquinoline, 1,10‐phenanthroline, benzothiazole, quinoline, and acridine, to give 1‐methylthio‐3‐(dihydroheteroaryl)azulenes in good yields. In the case of th
Two new series of 1,1 0 -carbonyl-bis[3-aryl(heteroaryl)-5-trihalomethyl-1H-pyrazoles], where aryl ¼ C 6 H 5 , 4-CH 3 C 6 H 4 , 4-FC 6 H 4 , 4-OCH 3 C 6 H 4 , 4-NO 2 C 6 H 4 , 4,4 0 -BiPh, 1-naphthyl, and heteroaryl ¼ 2thienyl and 2-furyl have been synthesized, in a one-pot methodology, from the rea