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Synthesis of 1-d- and 1-l-myo-inosityl 2-N-acetamido-2-deoxy-α-d-glucopyranoside establishes substrate specificity of the Mycobacterium tuberculosis enzyme AcGI deacetylase

✍ Scribed by Gillian M. Nicholas; Lisa L. Eckman; Pavol Kováč; Sarah Otero-Quintero; Carole A. Bewley


Book ID
108479340
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
224 KB
Volume
11
Category
Article
ISSN
0968-0896

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✍ Arun K. Sarkar; Rakesh K. Jain; Khushi L. Matta 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 1002 KB

Treatment of benzyl O-/?-n-galactopyranosyl-( 1+3)-2-acetamido-2-deoxy-4,6-O-isopropylidene-j3-D-glucopyranoside with tert-butylchlorodiphenylsiiane afforded the 6'-0-tert-butyldiphenylsilyl ether, which was converted into the 3',4'-0-isopropylidene derivative. Methylation and subsequent removal of