A library of 2,3-disubstituted benzofuran scaffold was developed by using intramolecular Wittig olefination and Friedel-Crafts acylation.
Synthesis of 1-aryl - 3, 3-disubstituted triazenes on ion-exchange resin support
β Scribed by Pranab J. Das; Susanta Khound
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 303 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
Diazonium tons h~vebeminmobilired on a cation exchanger followed by N-coupling on a Z-amine to give the 3,3-dlsubstltuted-1-aryltrlarenes as the only product. Reaction is clean and work up procedure simple.
π SIMILAR VOLUMES
Several l-(p-R-aryl)-3,3dimethyltriazenes are anodically oxidized at a Pt electrode in acetonitrile/O.l M tetrabutylammonium hexafluorophosphate in preparative-scale controlled potential bulk electrolyses. The overall oxidation process produces diazonium ions by cleavage of the N(2)-N(3) bond in the
The cross-coupling of 1-aryl-5-bromopyrazoles 4 with alkynes, vinyltins and arylboronic acids promoted by Pd(PPh 3 ) 4 aorded unsymmetrical 3,5-disubstituted 1-arylpyrazoles 5-8 in excellent yields. 1-Aryl-5bromopyrazoles 4 were prepared from their corresponding 1-arylpyrazolones 3 with PBr 3 in reΒ―