The synthesis of 10-fluorobenzo[a]pyrene
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Melvin S. Newman; Vinod K. Khanna
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Article
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2010
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Wiley (John Wiley & Sons)
β 162 KB
## Abstract The synthesis of 10βfluorobenzo[a]pyrene in four steps from 11βfluoroβ12βmethylbenz[a]anthracene is described. A current hypothesis concerning the metabolism which is responsible for the carcinogenic activity of benzo[a]pyrene, BP, maintains that BP is converted into isomers of 7,8βdih