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Synthesis of 1-(2-Hydroxyethyl)-1-nitrosourea and Comparison of Its Carcinogenicity With That of 1-Ethyl-1-nitrosourea2


Book ID
125829526
Publisher
Oxford University Press
Year
1979
Tongue
English
Weight
566 KB
Category
Article
ISSN
0027-8874

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Mutation spectra of N-ethyl-Nโ€ฒ-nitro-N-n
โœ Richardson, Katherine K. ;Crosby, Renae M. ;Skopek, Thomas R. ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 710 KB

DNA sequencing was used to determine the specific types of DNA base changes induced following in vivo exposure of Escherichia coli to the ethylating agent N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG) and the hydroxyethylating agent 1-(2-hydroxyethyl)-1-nitrosourea (HENU) using the xanthine guanine pho