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Synthesis, in-vitro Microbial and Cytotoxic Studies of New Benzimidazole Derivatives

✍ Scribed by Reddy S. Harisha; Kallappa M. Hosamani; Rangappa S. Keri

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
653 KB
Volume
342
Category
Article
ISSN
0365-6233

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✦ Synopsis

Abstract

Several new classes of benzimidazole derivatives were synthesized and evaluated for in‐vitro antimicrobial and cytotoxic activities. The results showed that all synthesized compounds exhibited moderate antimicrobial activity, and compounds 2, 4, and 13 displayed cytotoxic activity (as LD~50~) at the concentration 1Γ—10^–3^ M against Artemia salina.

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