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Synthesis, in vitro anticancer activity and in silico study of new disubstituted thiazolidinedione derivatives

✍ Scribed by Rêgo, Moacyr Jesus Barreto de Melo; Galdino-Pitta, Marina Rocha; Pereira, Daniel Tarciso Martins; da Silva, Juliana Cruz; Rabello, Marcelo Montenegro; Alves de Lima, Maria do Carmo; Hernandes, Marcelo Zaldini; da Rocha Pitta, Ivan; Galdino, Suely Lins; da Rocha Pitta, Maira Galdino


Book ID
121578325
Publisher
Springer-Verlag
Year
2014
Tongue
English
Weight
518 KB
Volume
23
Category
Article
ISSN
1054-2523

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Synthesis and in vitro Anticancer Activi
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## Abstract A novel series of fourteen substituted selenadiazoles has been synthesized and the compounds tested for their __in vitro__ antiproliferative and cytotoxic activities. The tests were carried out against leukemia (CCRF‐CEM), colon (HT‐29), lung (HTB‐54), and breast (MCF‐7) cancer cells. I