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Synthesis, hybridization properties and antiviral activity of lipid-oligodeoxynucleotide conjugates

โœ Scribed by Shea, Regan G.; Marsters, James C.; Bischofberger, Norbert


Book ID
111986824
Publisher
Oxford University Press
Year
1990
Tongue
English
Weight
707 KB
Volume
18
Category
Article
ISSN
0305-1048

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## Abstract New oligonucleotides with a longโ€chain linker (6,9โ€dioxaโ€3,12โ€diazatetradecaneโ€1,14โ€diyl) in their backbone were synthesized, and their hybridization properties were studied by measurement of their __T__~m~ curves and fluorescence spectra. The __T__~m~ analyses revealed that these oligo