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Synthesis, crystal structures, DNA binding and cytotoxicity of two novel platinum(II) complexes containing 2-(hydroxymethyl)pyridine and pyridine-2-carboxylate ligands

โœ Scribed by Icsel, Ceyda; Yilmaz, Veysel T.; Golcu, Aysegul; Ulukaya, Engin; Buyukgungor, Orhan


Book ID
121694952
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
811 KB
Volume
23
Category
Article
ISSN
0960-894X

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In an attempt to establish fundamental structure-activity relationships (SAR) of Pt/Pd-based anti-tumour compounds, we have recently designed monodentate pyridyl amide ligand containing central amide units which possess external metal co-ordinating pyridyl group and internal amide functionality. It