Synthesis, Crystal Structure of Cis-dioxo-catecholatotungsten(VI) Complex and Its NMR Studies on the Interaction with ATP

✍ Scribed by Lu Xiao-Ming; Liu Shun-Cheng; Jiang Ling; Mao Xi-An; Ye Zhao-Hui

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 375 KB
• Volume: 21
• Category: Article
• ISSN: 0256-7660
• DOI: 10.1002/cjoc.20030210614

✦ Synopsis

Hubei 430071 , China ci s -dioxo-catecholatotungsten ( VI ) complex anion [ w ( ~) 02-( 0 C J & 0 ) 2 ] 2was obtained with discrete protonated ethylenediamine ( NHtCH2CH2NH3) + cations by the reaction of tetrabutyl ammonium decatungstate with catechol in the mixed solvent of CH30H, CH3CN and ethylenediamine, and compared with its molybdenum analogue [MO'~'OZ(OC~&O)Z]~by crystal structure, UV , EPR. The results of the UV and EPR spectra show that tungsten is less redox active than molybdenum since the molybdenum is reduced from Mo(VI) to Mo(V) but tungsten stays in the original highest oxidized state Mo(VI) when they are crystallized from the solution above. It is worthy to note that [ W("')Oz( 0Cs&0)1]2shows the same coordination structure as its molybdenum analogue in which the metal center exhibits distorted octahedral coordination geometry with two cis-dioxocatecholate ligands and might have the related coordination structure feature with the cofactor of flavoenzyme because [ Mo(')02( OC6&O)2]3presented essentially the same EPR spectra as flavoenzyme. The N M R studies on the Interaction of the title complex with ATP reveal that the reduction of W ( M ) to W ( V ) occurs when the title complex is dissolved in D20 and the W ( V ) is oxidized again when ATP solution is mixed with original solution and the hydrolysis of the catecholato ligand take places at mean time Wing monitored by lH NMR and "C N M R spectra. Keywords ATP, DNA cleavage cis-dioxo-catecholatotungsten ( VI 1, EPR, NMR,