Synthesis, characterization and the effect of glucose-lowering of guanidino acid oxovanadium(IV) complexes

✍ Scribed by Ju-Tao Liu; Xiao-Hong Wang; Jian-Xin Li; Jing-Fu Liu

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 228 KB
• Volume: 22
• Category: Article
• ISSN: 0256-7660
• DOI: 10.1002/cjoc.20040220729

✦ Synopsis

Abstract

Two guanidino acid oxovanadium(IV) complexes have been synthesized. Preliminary tests in vivo have shown that the two title complexes all display lowering glucose activity in vivo to STZ‐rats. The effect of glucose‐lowering of guanidino acetic acid oxovanadium(IV) complex in vivo is higher than that of guanidino propanoic acid oxovanadium(IV) complex.