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Synthesis, Characterization and the Biological Activity of a Polyoxometalate-loaded Nanosize-liposome Complex

✍ Scribed by Yong Yang; Xiao-Hong Wang; Hong Xü; Xin Chen; Guo-Ming Liang; Jin Gou; Bin Li; Jing-Fu Liu; Xiao-Wang Du

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
76 KB
Volume
23
Category
Article
ISSN
0256-7660

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✦ Synopsis

Abstract

The polyoxometalate K~6~H[CoW~11~O~39~(CpTi)] (abbreviated as CoW~11~CpTi, Cp=η^5^‐C~5~H~5~) loaded nanosize‐liposome complex has been prepared and structurally characterized by elemental analysis, IR and UV spectra. The particle size of the complex was distributed in the range of 100–250 nm with the average diameter of 132.6 nm. The result showed that the polyoxometalate retained the parent structure after being encapsulated by liposome and liposomal encapsulation increased the antitumoral activity of the polyoxometalate.

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