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Synthesis, characterization and structural aspects of new haptens for PAHs

✍ Scribed by Yi Li; Mingming Yang; Yuanyuan Liu; Rongqing Wei; Xiaoning Liu; Fangshi Li


Book ID
108213354
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
961 KB
Volume
987
Category
Article
ISSN
0022-2860

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An extension of the transition state analogue (TSA) hapten approach for the elicitation of catalytic antibodies for acyl-transfer reactions is described. It is based on the enlistment of phosphorodithioate 1 as a stable mimic of the putative tetrahedral intermediate (TI-) formed during the base-cata