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Synthesis, characterization and release of cromoglycate from dextran conjugates

✍ Scribed by Anwen S. Williams; Glyn Taylor

Book ID
113365175
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
698 KB
Volume
83
Category
Article
ISSN
0378-5173

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Nystatin—dextran conjugates: Synthesis a
Nystatin—dextran conjugates: Synthesis and characterization
✍ Abraham J. Domb; Galina Linden; Itzhack Polacheck; Simon Benita 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 624 KB

The coupling of nystatin (Nys), a water-insoluble antifungal agent, to dextran via an imine or amine bond was systematically investigated. Dextran was first oxidized to dialdehyde dextran using potassium periodate, purified from the oxidizing agent, and reacted with Nys to form the Schiff base. The