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Synthesis, characterization, and reactions of selected multichalcone derivatives

✍ Scribed by Mousa Al-Smadi; Suhaib Mohammad

Publisher
Journal of Heterocyclic Chemistry
Year
2009
Tongue
English
Weight
99 KB
Volume
46
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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New multiarm aromatic chalcone derivatives 2a, 2b, 2c, 2d were prepared through cross‐aldol condensation reaction between multiarm aromatic ketones 1a, 1b, 1c, 1d and 4‐(dimethyl amino)benzaldehyde in basic medium. The multiarm aromatic chalcones 2a and 2c were able to undergo cyclization reactions when treated with hydrazine or any of it's derivatives to yield the corresponding pyrazolines 3a and 3c that were reacted with 2,3‐dichloro‐5,6‐dicyano‐1,4‐benzoquenone in benzene to yield the aromatic pyrazoles 4a and 4c, respectively. J. Heterocyclic Chem., 46, 201 (2009).

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