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Synthesis, Characterization and Electrochemical Behavior of Hepta-O-acetyl-β-lactosyl Isothiocyanate

✍ Scribed by Zhang Shu-Sheng; Yang Bo; Li Ji-Zhi; Li Xue-Mei; Jie Gui-Fen; Jiao Kui

Book ID
102095272
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
108 KB
Volume
23
Category
Article
ISSN
0256-7660

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✦ Synopsis

Abstract

A new compound of hepta‐O‐acetyl‐β‐lactosyl isothiocyanate has been synthesized and its structure was determined by X‐ray crystallography. The compound crystallizes in the orthorhombic system, with space group P2~1~2~1~2~1~ and cell dimensions of a=1.23282(7) nm, b=1.80012(10) nm, b=1.85230(10) nm, α=β=γ=90°, V=4.1107(4) nm^3^, and Z=4. The electrochemical experimental results indicate that both dsDNA and ssDNA had obvious reduction effect on the peak current of the title compound, which was bound to DNA mainly through electrostatic binding.

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