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Synthesis, characterization and biological activity of 2-(5-arylidene-2,4-dioxotetrahydrothiazole-3-yl)propanoic acid derivatives

✍ Scribed by Božić, Bojan; Rogan, Jelena; Poleti, Dejan; Rančić, Milica; Trišović, Nemanja; Božić, Biljana; Ušćumlić, Gordana


Book ID
121389904
Publisher
Elsevier
Year
2017
Tongue
English
Weight
879 KB
Volume
10
Category
Article
ISSN
1878-5352

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A series of 3-(4,6-disubtituted-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl) propanoic acid derivatives has been synthesized by condensation of thiourea, 5-(4-subtituted phenyl)-5-oxopentanoic acid and substituted aldehyde. The synthesized compounds were screened for their anti-inflammatory activity u