✦ LIBER ✦

Synthesis, characterization and antitumour studies of metal chelates of acetoacetanilide thiosemicarbazone

✍ Scribed by Sankar Jayasree; Kuttamath K. Aravindakshan

Publisher: Springer
Year: 1993
Tongue: English
Weight: 381 KB
Volume: 18
Category: Article
ISSN: 0340-4285
DOI: 10.1007/bf00136058

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✦ Synopsis

Complexes of transition metals with acetoacetanilide thiosemicarbazone, AatH2, have been prepared and characterized. The complexes were found to have the following stoichiometries: [Mn(Aat)(H20)2],; [Zn(Aat)(H20)2]; [M(Aat)(H20)], where M = Cd" or Hgn; [Cu(Aat)]n; [Ag(AatH)]; [M(AatH)2], where M = Co II or Ni 1I, and [Fe(Aat)CI(H20)],. The compounds have been studied for their possible antitumour activity against Ehrlich Ascites tumour cells in vitro.

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